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The incidence of cyclizine use during pregnancy

Cyclizine is an antihistamine that is used to treat nausea, vomiting, and dizziness. It is also used to treat vertigo (dizziness caused by a change in position). Cyclizine is in a class of medications called antihistamines. It works by blocking a natural substance (histamine) that your body makes during an allergic reaction.

Cyclizine is available in generic form and as the brand-name drug Marezine.

Generic drugs usually cost less. In some cases, they may not be available in every strength or form as the brand-name version.

Marezine is not available in every strength or form as the generic drug.

Cyclizine may also be used for purposes not listed in this medication guide.

Important Information

You should not use cyclizine if you are allergic to it, or if you have narrow-angle glaucoma, blockage in your digestive tract (stomach or intestines), or if you are unable to urinate.

Before taking this medicine

You should not use cyclizine if you are allergic to it, or if:

you have narrow-angle glaucoma;

blockage in your digestive tract (stomach or intestines); or

if you are unable to urinate.

To make sure cyclizine is safe for you, tell your doctor if you have:

asthma or other breathing disorder;

a history of starting or stopping breathing while you sleep (sleep apnea);

a blockage in your intestines;

kidney disease;

liver disease;

epilepsy or other seizure disorder;

diabetes; or

problems with your adrenal gland.

Cyclizine can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine.

Cyclizine should not be given to a child younger than 2 years old.

How should I take cyclizine?

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Cyclizine is usually taken every 6 hours. Follow your doctor’s instructions.

Do not take more or less of this medicine than prescribed or stop taking it even for a short time unless directed by your doctor. Doing so may make the medicine less effective.

To take cyclizine by mouth:

Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Swallow the capsule whole with a full glass of water.

Take this medicine with food or milk if it causes an upset stomach.

Shake the suspension well just before you measure a dose. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

The suspension may be placed directly into your mouth or mixed with water, milk, baby formula, fruit juice, or ginger ale just before you take it. Do not mix the suspension with any other liquids.

Use only the suspension form of this medicine for children younger than 2 years old. Carefully follow the mixing instructions, and use the suspension within 15 minutes of mixing. Throw away any mixed medicine that you do not use within that time.

Cyclizine doses are based on weight (especially in children and teenagers), and any changes may affect the dose.

Cyclizine can be habit-forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction.

Keep the medicine in a place where others cannot get to it. Selling or giving away this medicine is against the law.

The chewable form of this medicine may contain aspartame. If you have phenylketonuria (PKU) or any other condition that requires you to restrict your intake of aspartame (or phenylalanine), you should know that the chewable tablets contain aspartame that forms phenylalanine.

If you use this medicine long-term, you may need frequent medical tests at your doctor’s office.

Cyclizine is not approved for use by anyone younger than 2 years old.

Call your doctor if your vomiting does not stop, if you cannot drink fluids without throwing up, or if you have any signs of dehydration such as: dry mouth, thirst, dark urine, or feeling very tired or hot.

Do not stop taking cyclizine suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using cyclizine.

Store cyclizine at room temperature away from moisture and heat..Read Full Report

The pharmacokinetics of cyclizine in pregnant women

Cyclizine is an antihistamine that is used to treat nausea, vomiting, and dizziness. It is also used to treat motion sickness and vertigo. Cyclizine is available as a tablet, injection, and syrup. The half-life of cyclizine is 3-4 hours.

Pregnancy and lactation

There are no adequate studies in pregnant women. Cyclizine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Cyclizine is excreted in breast milk. Therefore, caution should be exercised when administering cyclizine to nursing mothers.

infants and children

There are no adequate studies in infants and children.

Elderly

There are no adequate studies in the elderly.

Renal impairment

There are no adequate studies in patients with renal impairment.

Hepatic impairment

There are no adequate studies in patients with hepatic impairment.

We used pregnancysicknesssuport.org.uk to write this article about cyclizine when pregnant. Read Full Report.